AOD9604 and Synapsin RG3

AOD9604 and Synapsin RG3

Nicotinamide adenine dinucleotide, or NAD for short, is essential to the inner workings of our cells. Similar to hormones, it is a molecule that participates in hundreds of processes that work to maintain healthy cellular function. NAD has become a highly researched molecule, especially in the field of aging.

AOD-9604 is a peptide from the sequence that makes up human growth hormone – specifically the lipolytic section. This is very telling of its function, as lipolytic refers to fat burning. While the peptide was originally thought to center around fat-burning capabilities, it has a variety of regenerative capabilities as well.

In this article, we will look at AOD 9604 and Synapsin RG3, a form of NAD+

Synapsin RG3 & NAD+

NAD+ is also an essential component of the citric acid cycle (or Krebs cycle), a cellular process that produces energy. This process takes place in the mitochondria of cells. This means that NAD+ is almost everywhere in the body. For energy production it reacts with O2 in mitochondria to produce ATP, the currency of energy. NAD is crucial to the aging process because the molecule is active in DNA repair, chemical stress, and inflammation.

Like many important hormones, NAD+, naturally decreases with age. This can lead to decreased energy levels and brain fog. To date, research highlights that increased levels of this molecule are associated with increased energy, cognition, focus and endurance,while decreased levels are associated with increased senescence (or aging).

There are a variety of treatments available that aim to increase naturally-circulating levels of NAD+. Modifying nutrition, sleep, activity, and meditation can all increase NAD+. Once you have maximized these, replacement options include intravenous, subcutaneous, and nasal spray. NAD+ is frequently combined with hormone balancing regimens. This provides a synergistic increase in energy.


What is Synapsin RG-3?

Synapsin® is an innovative nasal spray that contains ginsenoside RG3 and NAD, along with Vitamin B12. These ingredients support neurological and cognitive health. Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD) and is a source of Vitamin B3. Evidence indicates that nicotinamide riboside has unique properties as a Vitamin B3. Synapsin is able to be so effective because it is able to pass into the brain by easily passing the blood-brain barrier with an intranasal spray. Thus, synapsin may be able to help regulate NAD+ levels in the brain, something that declines with age and alongside most chronic neuroinflammatory diseases.

Benefits of Synapsin RG-3

Synapsin RG3 is a powerful anti-aging medicine that can help to:

  • Fight inflammation
  • Boost neuronal healing and regeneration
  • Reduce brain fog
  • Help mitochondria to become fully active and generate energy in the brain.
  • Aids sirtuins (SIRT1’s) which are regulators of metabolism.

How AOD-9604 Works

AOD-9604 was originally designed as an anti-obesity drug. The peptide itself is roughly about 10% of the total length of Growth Hormone. AOD-9604 does not have many of the harmful growth-inducing or insulin sensitivity effects that direct GH treatments. This provides effective treatment for osteoarthritis, cartilage damage, as well as high cholesterol.

AOD-9604 triggers the pituitary gland, which is also known as the body’s “master gland” because of its wide-ranging functions in the body. The pituitary gland works by secreting hormones throughout the body that trigger important mechanisms that help with healing, regeneration, metabolism, and more. The exciting aspect of AOD-9604 is its ability to mimic the best aspects of growth hormone treatment without presenting any of the harmful side effects of typical GH treatment.

A distinct advantage of AOD-9604 is that it does not activate many of the receptors that GH treatment typically does. This makes its effects so targeted and effective. Its specific structure allows it to interact with receptors that stimulate lipolysis, inhibit lipogenesis(fat generation) and increase overall triglyceride count.

The amino acids contained in AOD 9604 are the same as those found in naturally occurring hormones associated with growth.The chemical targets areas of the body where there are abnormally high levels of fat and increases the amount of fat the body uses to burn energy rather than carbohydrates.

Benefits of AOD-9604


AOD-9604 has been proven to have a variety of positive benefits that come along with none of the side effects of traditional hormone therapy. AOD-9604 is a peptide with a powerful mechanism that utilizes a potent chain from growth hormone responsible for triggering lipolysis, various forms of tissue growth and regeneration, as well as balancing metabolic effects. AOD-9604 works by stimulating the pituitary gland, which is responsible for secreting specific hormones that modulate the body’s metabolism, among other things.

  • Stimulates fat burning
  • Balances feelings of hunger
  • Regenerative properties
  • Reduce stubborn fat stores
  • No negative effect on blood sugar or tissue health
  • Improve bone density
  • Slows down the storage of fat cells

AOD-9604 has a variety of real-world applications that extend to both the healthy, everyday active individual as well as those who want a peptide that can aid in healthy bone growth and osteoporosis/arthritis treatment. It can help switch on another level of fat burning in the body and assist with the burning of stubborn fat stores. Additionally, it also can help reduce feelings of hunger and help you feel full more easily.

Some of its most important applications include:

  • Restart the metabolism of obese individuals. AOD-9604 can help obese individuals burn fat and can reverse some of the damaging effects of obesity on metabolism.
  • Used as combination therapy with BPC-157. Along with angiogenic and overall protective effects of BPC-157, used will receive fat-burning in addition to tissue regeneration, muscle-building capabilities, and decreases in inflammation throughout the body.
  • Fights off osteoporosis and osteoarthritis.

Who Are These Peptides For?

Together, AOD-9604 and Synapsin work as a powerful hormonal balancing team. These two substances are invaluable tools that can restore a healthy balance of hormones in the body and reset natural healing abilities as well as metabolic characteristics.

AOD’s ability to augment actions that are lost due to decreased Growth Hormone levels can help to significantly boost natural regenerative properties and metabolic functionality. In addition, Synapsin also provides a powerful effect of helping to rebalance the critically important NAD+ while providing nootropic benefits and additional metabolic improvements. Together, these two substances are a powerhouse hormonal balancing treatment that can help men and women rebalance their body’s natural healing properties and healthily fight the symptoms of aging.

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